VAP non drug preventive measures Download Table The New VAP Prevention Guidelines and the Importance of Oral Care VAP Bundle Ventilator Associated Pneumonia Ventilator Associated Pneumonia ( VAP) is a lung infection that occurs in patients who are on mechanical ventilation for more than 48 hours. A VAP bundle is a set of Preventive bundle approach decreases the incidence of ventilator associated pneumonia in newborn infants Journal of Perinatology