What's In Your Vape Juice? E Liquid Ingredients Explained EDGE Vaping Do you know what you're vaping? Propylene glycol (PG) and vegetable glycerin (VG) are the main liquids in vapes. When heated, these chemicals turn toxic and aren't safe to breathe. Vape Juice Ingredients: All You Need to Know What's in an e liquid or vape juice? The main ingredients are propylene glycol (PG) and vegetable glycerine (VG). These are solvents that are basically used to dissolve and carry the other ingredients.