How Much Glutathione Should I Take for Skin Whitening? Oral glutathione has been everyone on my timeline but does it actually work?! Looking at the data, its very modest to be honest. Id recommend sticking to what we know works fo hyperpigmentation in Glutathione Results Timeline: When To Expect Skin Benefits Does taking glutathione actually work?, Many people take glutathione supplements hoping for brighter, healthier skin., But heres the truth , Once glutathione is swallowed, it enters the stomach