Obesity pharmacotherapy in older adults: a narrative review of evidence International Journal of Obesity Retatrutide vs. Tirzepatide Best Weight Loss Peptide? Cagrilintide, an amylin analogue, is a promising medication for weight loss by enhancing satiety, delaying gastric emptying, and suppressing appetite. In my patients, I have also seen increased Comparative Efficacy and Safety of Semaglutide, Cagrilintide, and CagriSema in Adults with Overweight or Obesity: A Bayesian Network Meta Analysis Journal of Clinical Question