B12 vitamin Store Intramuscular vs Subcutaneous Injections for vitamin B12 supplements. Learn how to administer your own SubQ (subcutaneous) injections at home with confidence. Our step by step guide covers everything you need to know, from preparing your supplies to safely injecting the medication. Our B12 vitamin Store How to Perform a Subcutaneous Injection of Vitamin B12 Subcutaneous (SC) and Intramuscular (IM) Injections Must Knows for Subcutaneous administration: Pinch skin with non dominant hand and hold syringe with dominant hand Always inject: 2 inches away from umbilicus (for abdomen) 3 inches