Don't be foolede cigs or vapes may be less harmful than cigarettes, but less harmful doesn't mean safe. Vapes can contain harmful substances including nicotine, heavy metals like lead, volatile organic compounds and e liquide CBD OG Kush Latest Cochrane Review finds high certainty evidence that nicotine e cigarettes are more effective than traditional nicotine replacement therapy (NRT) in helping people quit smoking Cochrane Side effects of vaping without nicotine